DARPA Information Innovation Office (I2O)

BTO is hosting a virtual Industry Day for the D2-Sprint prize competition, which seeks autonomous algorithms to enable hands-free DD Form 1380 documentation and real-time TCCC clinical decision support using passive sensor data. | See Event

DARPA TTO will host an Industry Day to brief potential proposers on the objectives of a future Next Generation Hypersonic Cruise Missile (NGHCM) program. This event precedes the planned release of a Program Solicitation (PS). Advance registration is required to attend. | See Event

Seeks to develop and demonstrate a robust methodology to localize, characterize and model upstream noise and flow disturbances in hypersonic wind tunnels. | See Topic

This topic seeks to develop a fuel-flexible spacecraft electric propulsion system. | See Topic

This topic seeks to develop and demonstrate novel nanofabrication hard-mask materials. | See Topic

We will host a hybrid Proposers Day in support of the Atomically Precise Molecules (APM) solicitation in Arlington, Va., and via webcast on Sept. 30, 2026, from 9 a.m. to noon ET. | See Event

BTO is hosting a Proposers Day for the potential proposer community for the High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators program . | See Event

TTO is sponsoring a Proposers Day to provide information to potential proposers on the objectives of the TTO Office-Wide (OW) Solicitation. | See Event

BTO will host a virtual Industry Day for potential competitors in the DARPA Surgical Competition (DSC) on Nov. 4, 2026.| See Event

This SBIR seeks to combine such capabilities into a single, portable, integrated intervention and delivery platform for resuscitation, cardiovascular and lung support. | See Topic

DARPA will host an Industry Day in support of the BEAMERS program on Sept. 30, 2026, in Arlington, Va. This event will be conducted in two parts: Government presentation (SECRET) and a poster session (CUI). | See Event

This topic seeks to develop and demonstrate capability with autonomous medical triage systems to recognize chemical toxidromes and physically deliver the corresponding antidote or life-saving intervention. | See Topic

This topic seeks a software tool that forecasts casualty loads and evaluates lifesaving medical response options during large-scale emergencies in austere, comms-denied settings. | See Topic

This Broad Agency Announcement (BAA) seeks revolutionary research ideas for topics not being addressed by ongoing IPTO programs or other published solicitations. | See IPTO

Young Faculty Award program aims to identify and engage rising stars in junior research positions in academia and equivalent positions at non-profit research institutions. | See YFA program

MXO is soliciting innovative proposals in the areas of new synthesis techniques for polymeric materials and nonlinear optical (NLO) materials. | See Program

DSO is requesting information on the current state of the art and technological limitations of solid-state direct thermal-to-electric energy conversion technologies. | See DSO

This topic seeks to develop, integrate, and flight-test a high-altitude (~40,000 ft), high-speed (~400 knots) airborne geologic sensing system. | See Topic

DSO is issuing a Disruption Opportunity (DO), inviting submissions of innovative basic or applied research concepts in the technical domain of accelerated materials testing and prediction for concrete. | See Program

IPTO is sponsoring a Proposers Day on Oct. 1, 2026, in Arlington, Virginia, with unclassified and classified sessions for Intrinsic Market Resilience (IMR), a possible future program. | See Event

The primary intent of this RFI is to inform industry of a potential new DARPA program and to encourage innovative contractor/subcontractor teaming arrangements prior to formal solicitation. | See Office

The IMR program aims to develop repair methods to protect essential economic sectors against devastating attacks that exploit the public interfaces of modern markets. | See Program

DSO is “shopping” the ERIS Marketplace for game-changing, foundational mechanisms capable of fundamentally disrupting legacy thermodynamic limits across diverse DoW application spaces. | See ERIS

This topic seeks to mature and commercialize revolutionary Unmanned Aircraft System (UAS) subsystem designs capable of breaking the 4:1 payload-to-weight ratio. | See Topic

We are soliciting innovative proposals for the development of a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. | See Program

This topic seeks to develop and demo a robust framework and tool suite building on automated algorithm discovery tools that will enable the seamless integration of discovered algorithms with the scientific and engineering workflow. | See Topic

This topic seeks to develop and demo a modular, open-architecture AUVs for rapid payload swapping, collaborative fleet deployment, and resilient undersea navigation. | See Topic

DARPA is hosting a Proposer Day for the Firefox program, which aims to pave the way for high-speed, scalable neural interfaces that may eliminate the need for invasive surgery. | See Event

We are soliciting innovative proposals in this technical area: physics and nonlinear control of inertial measurement units appropriate for tactical and unmanned missions for the PINPOINT program. | See DSO

This topic seeks to develop real-time, networked surveillance technology for accurate, automated New World screwworm detection. | See Topic

This topic seeks to demonstrate a capability that noninvasively detects and localizes occult (internal) non-compressible hemorrhage outside of a hospital. | See Topic

This topic seeks to develop a testbed utilizing economic frameworks to benchmark AI biases in dynamic environments. | See Topic

DSO is issuing a Disruption Opportunity, inviting submissions of innovative basic or applied research concepts in the technical domain of targeted neuroplasticity. | See Program

This seeks to develop and demonstrate an automated, species-agnostic cell culture platform to rapidly establish viable cell lines (including iPSCs) from diverse non-model species, enabling the validation of genetic-biocontrol technologies. | See Topic

STO will host a Proposers Day in support of the Unison program on Nov. 5, 2026 in Arlington, Va. | See Event

DARPA is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. | See Program

IPTO is sponsoring a Proposers Day on Dec. 10 in Arlington, Va., in support of the anticipated critical infrastructure resilience program, Nassau. | See Event

DARPA is soliciting approaches to overcome key technological hurdles to develop a 100-channel, non-invasive BCI with 50-micron spatial and 100-microsecond temporal resolution. | See Program

DARPA will host an in-person Proposers Day in support of the Protein Palace program on Nov. 17, 2026, in Arlington, Va. | See Program

DARPA intends to host future workshops to determine the commercial impact of future utility-scale quantum computers. Any future QC-AW RFI's describing the workshop will be made available at https://sam.gov. | See QBI

The I2O BAA covers four thrust areas with 'Fighting in the Information Domain' directly addressing cognitive warfare and information operations: cognitive and semantic operations, digital artifact tracking (deepfake and synthetic media forensics), adversarial influence, and transport mechanisms. The BAA explicitly seeks 'unconventional approaches capable of delivering decisive information and computational advantage.' Rolling abstract submissions required before invitation to full proposal. Temporarily paused May–August 2026 for strategic realignment; expected to reopen August 2026.

The IMR program aims to develop repair methods to protect essential economic sectors against devastating attacks that exploit the public interfaces of modern markets. | See Program

DSO is issuing a Disruption Opportunity (DO) in the technical domain of developing novel metrology for understanding wave propagation in compressible fluids. | See DO

MXO seeks information on compact, rugged millijoule-class ultra-short pulsed lasers. | See MXO